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Piazza dell'Unità 24, Rome, 00192 (show map)
Guest houses Overview

Lock in a great price now and relax with our Price Guardian working for you
Hotel prices fluctuate. Book now, we will check prices each day for you and then let you know how to re-book if an even better price becomes available.Rooms List
Setup a Price Alert for Domus Serafino
Each day we'll check prices and send you an email for your selected dates at Domus Serafino. If you don't have specific dates but would like to check prices for say next weekend or say next month we can check the price too.
When the hotel goes on sale you will know straight away from the daily email and be able to book with confidence that you've got excellent value.
Facilities of Domus Serafino
General
WiFi everywhere
Services
Free WiFi, Internet services, WiFi
Front-desk/reception area services
Safety deposit box
Miscellaneous
Air conditioning, Heating, Lift, Non-smoking rooms, Non-smoking throughout
Room facilities [ These may vary room to room ]
Air Conditioning, Bathroom, City view, Clothes rack, Coffee machine, Desk, Electric kettle, Flat-screen TV, Free toiletries, Hairdryer, Hardwood/Parquet floors, Heating, Iron, Ironing Facilities, Private entrance, Safety Deposit Box, Shower, Soundproofing, Tea/Coffee Maker, Toilet, Towels, TV, Upper floors accessible by lift, Upper floors accessible by stairs only, View, Wardrobe/Closet
Hotel Policies
Check-In
From 12:00:00 hours
Check-Out
-10:00:00 hours
Cancellation / Prepayment
Cancellation, prepayment and 'book now pay later' policies vary according to room type. Please check the room conditions when selecting your room above.
Accepted credit cards
The hotel reserves the right to pre-authorise credit cards prior to arrival.
The fine print
Late check cost is 20 euro (late check in is from 21:00)Please inform in advance of your expected arrival time. You can use the Special Requests box when booking, or contact the property directly with the contact details provided in your confirmation.
Guests are required to show a photo identification and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.
Traveller reviews

“Clean and comfortable. Very friendly host”
17 Jul 2025
Very clean and comfortable. Marco was incredible. Very friendly and he also proposed some very good places to go. He also let us stay in the lobby for a while when we returned after our check out to retrieve our luggages in order to charge our phones. I cant recommend it enough

“Will come back here again for sure”
06 Jul 2025
It is really clean and cozy. There is a common area with a kitchen that makes the whole place bigger

“The host, Marco is so kind, polite and helpful. May God bless him”
04 Jul 2025
The property was exceptionally clean and gave off a five-star hotel vibe. It’s also just a few minutes away from Vatican City. My husband is very particular when it comes to hotels, but as soon as we arrived, he loved the place—so much so that we ended up extending our stay. Highly recommended!

“Very nice”
01 Jul 2025
There was a lift, which was very helpful with luggage. Having a coffee machine and access to a fridge also great.